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A wide variety of assay products for identifying and analyzing of proteins and their functions. Products utilize various detection methods and sample types and can be used for applications including medical, cellular, molecular, and protein research.
A plasmid DNA used to reduce the amount of an expression vector or reporter vector in mammalian cell transfection without reducing the overall amount of DNA.
FluoroTect Green(Lys) in vitro Translation Labeling System allows fluorescent labeling and detection of proteins synthesized in vitro. It is based on a lysine-charged tRNA labeled at the epsilon position of the lysine with the fluorophore BODIPY-FL.
MEK Inhibitor U0126 is a chemically synthesized organic compound that inhibits activation of MAPK (ERK 1/2) by inhibiting the kinase activity of MAP Kinase Kinase (MAPKK or MEK 1/2).
The ADP-Glo™ Max Assay is a luminescent ADP detection assay that provides a universal, homogeneous, high-throughput screening method to measure ATPase or kinase activity by quantifying the amount of ADP produced in a reaction.
Allows propagation and banking of the ADCC Bioassay Effector Cells. Product includes two frozen vials of Bio-Glo™ Luciferase Assay System reagent at 2 x 107 cells/mL and 0.65mL/vial. One vial should be used to create a cell bank, and the other should be reserved as backup.
BACE1 (beta-secretase) is a key enzyme involved in the production of amyloid beta-peptides found in extracellular amyloid plaques of Alzheimer's disease (AD).
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Recommended for use as a control with all Fc Effector Bioassay Core Kits. ADCC Reporter Bioassay provides a biologically relevant and specific mechanism-of-action-based measure of ADCC without the complex workflow and variability inherent in primary cell-based assays.
Apoptosis Phospho-Specific Array includes 247 highly specific and well-characterized phosphorylation antibodies i related to the proteins regulating apoptosis.
Generate N-Terminal Fusions with N-Terminal Secreted NanoLuc™ Luciferase. The pNLF1 Vectors use traditional cloning with a multiple cloning site to generate N-terminal fusions to NanoLuc™ luciferase. All vectors contain a mammalian selectable marker to create a stable line.
The pNLCoI Vectors comprise a second-generation coincidence reporter vector system that allow expression of both firefly luciferase (luc2) and NanoLuc Luciferase fused to a PEST destabilization domain (NlucP) from the same mRNA transcript.
Generate N-Terminal fusions to NanoLuc™ Luciferase Reporter. The pFN31A and pFN31K Nluc CMV-neo Flexi™ Vectors use a directional cloning method based on two rare-cutting restriction enzymes, SgfI and PmeI, and contain a mammalian selectable marker to create a stable line.